垂体疾病单中心数据库建设及应用

Establishment and application of a single-center pituitary disease database

目的描述北京协和医院(PUMCH)垂体疾病数据库的特征及人口统计学结果。方法描述性分析1978年-2018年收入PUMCH垂体疾病数据库的垂体疾病手术病人的基本信息及诊断信息。结果该数据库共收入8324例,男3240例(38.92%),女5084例(61.08%);平均首诊年龄(41.37±14.08)岁。病人包含32个省份,集中于华北、华东、东北地区。共收录11种垂体疾病,垂体腺瘤占比99.12%(8253/8324)。结论 PUMCH垂体疾病数据库是中国最大的垂体疾病单中心数据库,该数据库的建立有助于研究中国垂体疾病诊疗现状、开展流行病学调查和临床试验。

Objectives To describe the feature and demographic results of pituitary diseases database in Peking Union Medical College Hospital（PUMCH）. Methods Basic information and diagnostic message of surgical patients with pituitary disease from 1978 to 2018 in PUMCH pituitary disease database were descriptively analyzed. Results A total of 8324 patients were included in th database, 3240（38.92%） were male and 5084（61.08%） female. The age at initial diagnosis was 41.37 ± 14.08 years old. The patients came from 32 provinces, concentrated in the North China, East China and Northeast China regions. Eleven categories of pituitary diseases were recorded, with pituitary adenomas accounting for 99.12%（8253/8324）. Conclusions PUMCH single-center pituitary disease database is the largest single center database for pituitary diseases in China, which is usefull to study the current situation of pituitary disease diagnosis and treatment, make the epidemiological investigation and clinical trials.