1-溴丙烷使用企业职业卫生调查

Occupational health investigate of 1-bromopropane used in a factory

目的对1-溴丙烷（1-bromopropane，1-BP）使用企业进行职业卫生调查，了解1—BP对职业接触人群健康的影响。方法在2016年12月至2017年12月调查企业生产工艺和工人作业特征，进行空气中1-BP浓度检测，分0-,6、12月，3个时间节点收集15名接触纯1-BP工人的职业健康资料，分析职业接触1-BP对健康的影响。结果该使用纯1-BP的工作场所，工作场所空气浓度均值为26．8mg／m^3，个体接触水平为29．7～63．4mg/m^3。职业健康监护资料显示，白细胞计数（WBC）、红细胞计数（RBC）、天门冬氨酸氨基转移酶（AST）、丙氨酸氨基转移酶（ALT）在0、6、12月中3次结果比较，差异有统计学意义（P〈0．05o结论12月观察期内，1-BP职业暴露引起作业工人外周血红细胞和白细胞计数，以及谷丙转氨酶水平变化，但未超出正常参考范围。

Objective To investigate the occupational health survey of l-brominepropane （1-BP） enterprises and understand the impact of 1-BP on the health of occupational exposure population. Methods The occupational health data of 15 1-BP workers were collected from 3 time nodes in 0 months, June and December, and the effects of occupational exposure to 1-BP on health were analyzed. Results In the workplace with pure 1-BP, the mean air concentration in the workplace was 26.8 mg/m^3, and the personal contact level was 29.7 to 63.4 mg/m^3. The occupational health monitoring data showed that white blood cell count （WBC）, red blood cell count （RBC）, aspartate aminotransferase （AST） and alanine aminotransferase （ALT） were compared in 0 months, June, and 12 months, the difference was statistically significant （P〈 0.05）. Conclusion During the 12 months observation period, the occupational exposure to 1-BP caused the number of peripheral blood erythrocyte and leukocyte count and the level of alanine transaminase in the workers, but it did not exceed the normal reference range.