2631例呼吸道感染患者肺炎支原体及合并病毒感染分析

Analyse of Mycoplasma pneumoniae and combined virus infection in 2631 cases of respiratory tract infection

目的回顾性分析2 631例可疑呼吸道感染患者血清中肺炎支原体(MP)与病毒独立检出情况及合并感染情况,为呼吸道感染患者临床合理治疗和预防提供依据。方法应用间接免疫荧光法(IIFA),对2 631例呼吸道感染患者的血清同时进行9项常见呼吸道感染病原体检测,统计分析检测结果。结果 2 631例患者中MP检出率21.28%,病毒检出率10.22%。MP阳性合并病毒感染百分率20.71%,病毒感染合并MP百分率39.03%(P<0.05)。MP合并病毒感染以MP合并Flu B感染最常见,占2.43%。不同年龄组中,儿童组(<18岁)MP检出率最高,占27.52%。不同年龄组MP合并病毒感染,也以儿童组占最高,占25.07%(P<0.05)。不同性别组中,男性MP检出率18.74%,女性MP检出率25.19%(P<0.05);男性MP合并病毒感染率8.75%,女性MP合并病毒感染率11.96%(P<0.05)。不同季节组,春季、夏季MP检出率分别为24.15%、24.46%,较秋季、冬季高(P<0.05);春、夏季MP合并病毒感染率分别占5.89%、7.85%,也较秋冬季高(P<0.05)。结论 MP为本地区呼吸道感染主要致病原,且MP合并病毒感染机率高,随年龄不同、流行季节不同而有一定的流行规律,对于呼吸道感染的诊断具有重要意义。

Objective Retrospective analysis of Mycoplasma pneumoniae（MP）,virus and MP and virus co-infection in2 631 cases suspected respiratory tract infection,and provide reasonable basis for the clinical treatment and prevention ofrespiratory tract infection.Methods Indirect immunofluorescence assay（IIFA） was used to detect the 9 commonpathogens of respiratory infections in 2 631 patients with respiratory tract infection and the results were statistically analyzed.Results The detection rate of MP was 21.28% in 2 631 patients,and the virus detection rate was 10.22%.The percentageof MP-positive co-infected with virus was 20.71%,and the percentage of virus combined with MP-infection was 39.03%（P〈0.05）.Among MP-virus coinfection,the most common coinfection was MP combined with Flu B infection,accounting for2.43%.Among the different age groups,the detection rate of MP in the children group（〈18 years old）was the highest,accounting for 27.52%.MP infection in different age groups was also highest in the children group,accounting for 25.07%（P〈0.05）.Among males and females,the male MP detection rate was 18.74% and the female MP detection rate was25.19%（P〈0.05）.The male MP infection rate was 8.75%,and the female MP infection rate was 11.96%（P〈0.05）.Thedetection rates of MP in spring and summer were 24.15% and 24.46%,respectively,which were higher than those inautumn and winter（P〈0.05）.The infection rates of MP combined with virus in spring and summer accounted for 5.89% and7.85%,respectively,which was also higher than those in autumn and winter（P〈0.05）.Conclusion MP was the mainpathogen of respiratory infection in this region,and the probability of MP infection combined with virus was high.It had acertain epidemic pattern with different ages and different epidemic seasons,which was of great significance for the diagnosisof respiratory infection.