糖尿病足患者感染病原菌特点及耐药性分析

Characteristics of pathogenic bacteria and analysis of drug resistance in diabetic foot patients

目的分析糖尿病足患者感染病原菌的特点及耐药性。方法选取医院内分泌科收治的糖尿病足感染患者85例,对其足部分泌物进行细菌分离、鉴定及药敏分析。结果 85例糖尿病足感染患者分离出114株病原菌,其中革兰阳性菌占64.0%,阴性菌占36.0%。单一菌感染76.5%,混合感染23.5%。革兰阳性菌中以金黄色葡萄球菌、凝固酶阴性葡萄球菌常见,对喹诺酮类耐药率高,未发现耐万古霉素菌株。阴性菌中常见的有大肠埃希菌、肺炎克雷伯杆菌。多药耐药率高,未发现耐亚胺培南菌株。结论对糖尿病足感染患者应及时行分泌物培养及药敏试验分析。

Objective Analysis of pathogenic bacteria and diabetes resistance of patients with diabetic foot infection.Methods 85 patients with diabetic foot infection admitted to the hospital＇s endocrinology department were selected for bacterial isolation,identification and drug susceptibility analysis of their foot secretions. Results Among the 85 patients with diabetic foot infection,114 strains were isolated,of which Gram-positive bacteria accounted for 64. 0% and negative bacteria accounted for 36. 0%. Single infection was 76. 5% and mixed infection was 23. 5%. Staphylococcus aureus and coagulase-negative staphylococci are common among Gram-positive bacteria,and the resistance rate to quinolones is high. Vancomycin-resistant strains are not found. Escherichia coli and Klebsiella pneumoniae are common among negative bacteria. The rate of multidrug resistance is high and no imipenem-resistant strains have been found. Conclusion Patients with diabetic foot infection should be promptly carried out secretion culture and drug susceptibility test analysis