孤独症谱系障碍儿童共患睡眠障碍相关危险因素的研究进展

Research progress on risk factors for children comorbid autism spectrum disorder and sleep disorder

孤独症谱系障碍(ASD)是一组发生于儿童发育早期的神经障碍性疾病,近年来发病率较高。睡眠障碍是ASD儿童常见的一种共患疾病,其严重程度不仅能加重患儿的行为问题,影响学习记忆,降低癫痫阈值,而且增加照顾者的压力。因此,本文将从生物学因素、ASD儿童的核心症状、共患疾病和环境因素进行综述,为更好地理解、预防和早期干预ASD儿童的睡眠问题提供依据。

Autism spectrum disorder（ASD）is a group of neurodevelopmental disorders that occurs in early childhood and has high incidence in recent years.Sleep disorder is a common comorbidity of ASD children,and the severity can not only exacerbate behavioral problems in children,affect learning and memory,lower the threshold of epilepsy,but also increase the pressure on caregivers.Therefore,this article reviews the biological factors,core symptoms,comorbidity and environmental factors of ASD children in order to better understand,prevent and give early intervention on sleep disorder in ASD children.