摘要
延胡索酸酯治疗中重度银屑病患者,安全有效。延胡索酸酯通过影响T细胞、树突状细胞、中性粒细胞、角质形成细胞和内皮细胞等参与机体的免疫过程。本文综述了延胡索酸酯治疗银屑病的相关机制及其在临床中的应用。
Fumaric acid ester( FAE) is effective and safe for treating moderate to severe psoriasis. FAE is involved in immune defense process by influencing various kinds of cells,such as T cells,dendritic cells,neutrophil,keratinocytes and endothelial cells. The pathogenesis and clinical application of FAE in the treatment of psoriasis is reviewed.
作者
曾菁莘
张丽丹
刘炜钰
罗权
ZENG Jingxin;ZHANG Lidan;LIU Weiyu;LUO Quan(Guangzhou Institute of Dematology, Guangzhou 510095, China;Guangzhou Medical University, Guangzhou 510182, China)
出处
《中国麻风皮肤病杂志》
2018年第6期370-373,共4页
China Journal of Leprosy and Skin Diseases
基金
广东省医学科研基金(编号:A2015305)
广州市科技计划一般项目(编号:2016007010340)
广东省医学科研基金(编号:A2016542)
关键词
延胡索酸酯
银屑病
富马酸二甲酯
fumaric acid esters (FAE)
psoriasis
dimethylfumarate (DMF)