IVIM扩散加权成像在前列腺疾病中的研究进展

Research advances of intravoxel incoherent motion diffusion-weighted imaging in prostatic diseases

早发现、早诊断和早治疗对前列腺癌患者的预后有重要意义。体素内不相干运动(IVIM)成像可以区分组织水分子扩散和微循环灌注两种效应,能更准确反映组织的病理生理变化。IVIM在肿瘤领域具有很大的潜力,可以用于肿瘤的检出、诊断、分期、监测疗效及预后评估。本文重点就IVIM的原理及在前列腺疾病的研究进展予以综述。

Earlier detection, diagnosis and treatment are of great importance for the prognosis of patients with prostate cancers. Intravoxel incoherent motion（IVIM） can distinguish the diffusion of water molecules in tissue and microcirculation perfusion, and reflect the pathophysiological changes of tissue more accurately. IVIM has great potential as a tool in the treatment of cancer patients, achieving earlier detection, diagnosis, staging of cancer, therapeutic effect monitoring and prognosis evaluation. The principles of IVIM and its application and advances in prostate diseases are mainly summarized in this review.