摘要
桑皮苷是传统中药桑白皮中一种主要的二苯乙烯苷类活性成分,存在于治疗痛风、关节炎和风湿病的传统中医处方中,其主要作用是利尿和减轻水肿。近年来,国内外学者对桑白皮主要活性成分的药理活性研究较多,尤其是在借助现代药理学的技术和方法后,桑皮苷的各种生物活性和药理作用逐渐被发现。该文从药理作用角度对桑皮苷的相关研究进行综述,以期为桑皮苷的进一步研究开发和应用提供参考。
Mulberroside,a glycosylated stilbene,is the main bioactive constituent of white mulberry root-bark(Sangbaipi). It is widely used in many famous traditional Chinese medicine prescriptions to treat gout,arthritis,and rheumatism through purging diuresis and relieving edema. In recent years,the pharmacological activity of mulberroside has drawn extensive attention.With the utilization of the techniques and methods of modern pharmacology,a variety of biological activity and pharmacological effects of mulberroside are discovered gradually. The recent progress in the research on pharmacological effects of mulberroside was reviewed in this paper to provide reference for the further development and comprehensive utilization.
作者
黎玉华
温金华
周健
钟国平
黄民
毕惠嫦
魏筱华
LI Yu-hua;WEN Jin-hua;ZHOUJian;ZHONG Guo-ping;HUANG Min;BI Hui-chang;WEI Xiao-hua(Dept of Pharmacy the First Affiliated Hospital, Nanchang University, Nanchang 330006, China;Sckool of Pharmaceutical Sciences, Sun Yat-See University, Guangzhoo 510006, China)
出处
《中国药理学通报》
CAS
CSCD
北大核心
2018年第6期749-752,共4页
Chinese Pharmacological Bulletin
基金
国家自然科学基金资助项目(No 81660618)
关键词
桑皮苷
消炎镇痛
抗氧化
降血脂
药理作用
研究进展
mulberroside
anti-inflammation
anti-oxidation
hypolipidemic
pharmacological effects
research progress