超声检查在评价间质性肺疾病患者肺及心脏受损中的价值分析

Value of ultrasonography in assessing lung and heart damage in patients with interstitial lung disease

目的探索超声检查肺及心脏对评价间质性肺疾病患者肺和心脏受损情况的反映程度,明确超声检查对心脏受损的反映价值。方法选取2013年2月至2016年6月于兵器工业卫生研究所521医院接受治疗的92例间质性肺疾病患者作为研究对象,对患者进行肺、心脏超声检查。观察患者心、肺功能、第1秒用力呼气容积(FEV1)、用力肺活量(FLV)、呼气峰值流速(PEF)、最大通气量(MVV)、心脏血液流速、动脉血管内膜增厚、肺动脉高压值、左心室射血分数(LVEF),并进行相关性分析。结果间质性肺疾病患者中等损伤(41.30%)和严重损伤(42.39%)患者较多。肺功能检测发现,观察组患者FEV1/FLV为(73.24±14.25)%,PEF为(169.43±25.21)mL/s,MVV为(3 635.25±36.31)mL。心脏功能检测发现,心脏血液流速为(0.43±0.11)m/s,动脉血管内膜增厚(0.78±0.16)mm,肺动脉高压(28.15±9.51)mm Hg,LVEF(48.34±13.07)%。除动脉血管内膜增厚数据高于正常值外,其他数据均低于正常值。结论超声检查能客观反映间质性肺疾病患者的心肺状态,间接反映患者肺和心脏受损程度、肺功能变化情况及心功能情况,为临床治疗提供有效信息。

Objective To explore the value of ultrasound examination of lung and heart in assessing the changes of lung and heart in patients with interstitial lung diseases ,and to determine the value of ultrasonog-raphy in response to heart damage .Methods A total of 92 patients with interstitial lung disease who were treated in Weapons Institute of Industrial Hygiene 521 Hospital from February 2013 to June 2016 were en-rolled in the study as the research subjects .The patients underwent echocardiography examination for the lungs and heart .The lung function ,heart function ,maximum expiratory volume first seconds expiratory vol-ume （FEV1 ） ,forced vital capacity （FLV） ,peak expiratory flow rate （PEF ） ,maximal ventilator volume （MVV） ,blood flow to the heart ,arteries ,pulmonary hypertension ,left ventricular function index （LVEF） were observed and correlation analysis was carried out .Results The study found that moderate lung injury （41 .30％ ） and severe injury （42 .39％ ） were more common in patients with interstitial lung disease .In the de-tection of lung function ,the FEV1/FLV ratio was （73 .24 ± 14 .25）％ ,PEF was （169 .43 ± 25 .21） mL/s ,MVV was （3635 .25 ± 36 .31） mL .In terms of cardiac function ,heart blood flow velocity was （0 .43 ± 0 .11） m/s ,ar-terial intimal thickening was （0 .78 ± 0 .16） mm ,pulmonary arterial hypertension was （28 .15 ± 9 .51） mm Hg , LVEF was （48 .34 ± 13 .07）％ .Except arterial intima thickening data was higher than the normal value ,other data were lower than the normal value .Conclusion Ultrasound examination can reflect the changes of lung and heart effectively in evaluating the patients with interstitial lung disease ,and has an objective reflection on the heart and lung states of the patients .In addition ,ultrasound examination can indirectly reflect the degree of lung and heart damage ,the change of lung function and the function of the heart ,so as to provide effective in-formation for the clinical treatment .