骨髓细胞形态检验在难治性贫血与巨幼细胞性贫血鉴别中的临床价值

Clinical value of bone marrow cell morphology test in the identification of refractory anemia and megaloblastic anemia

目的研究骨髓细胞形态检验在难治性贫血与巨幼细胞性贫血鉴别中的临床价值。方法随机选取2015年5月至2017年5月我院收治的30例难治性贫血患者为RA组,30例巨幼细胞性贫血患者为MA组。两组患者均接受骨髓细胞形态检验。统计分析两组患者的外周血象特征、骨髓细胞形态检验结果、巨幼变红细胞胞体直径。结果 RA组患者的有核红细胞PAS阳性率显著高于MA组(P<0.05),红系病态、粒系病态、淋巴样小巨核比例均显著高于MA组(P<0.05),巨幼变原始红细胞、巨幼变早幼红细胞胞体直径均显著小于MA组(P<0.05)。结论骨髓细胞形态检验在难治性贫血与巨幼细胞性贫血鉴别中的临床价值高。

Objective To study the clinical value of bone marrow cell morphology test in the differential diagnosis of refractory anemia and megaloblastic anemia. Methods Thirty cases of patients with refractory anemia from May 2015 to May2017 in our hospital were randomly selected as RA group and 30 cases of patients with megaloblastic anemia were selectedas MA group, the two groups received bone marrow cell morphology test. The peripheral blood, bone marrow cell morphology test results, megaloblastic changes of red blood cell soma diameters of the two groups were statistically analyzed. ResultsThe positive rate of PAS cells of the RA group was significantly higher than that of the MA group（P〈0.05）; the proportionsof erythroid, granulocytic and lymphoid megakaryocytes were significantly higher than those of the MA group（P〈0.05）;the diameters of erythrocyte body of megaloblastic primordial erythrocyte and early megaloblastic erythrocyte were significantly smaller than the MA group（P〈0.05）. Conclusion The clinical value of bone marrow cell morphology test in theidentification of refractory anemia and megaloblastic anemia is high.