61例单胎胎儿生长受限临床分析

Clinical analysis of 61 cases of single fetal growth restriction

目的探讨胎儿生长受限(FGR)的病因、监测、治疗以及妊娠结局。方法收集我院2014年7月至2017年7月61例单胎FGR孕妇的临床资料,根据发现FGR时的孕周将其分为<28周组和≥28周组,对两组的临床资料进行回顾性分析。结果两组孕妇年龄、产次、有无合并症、胎盘脐带异常、治疗人数、治疗有效率、阴道分娩人数、新生儿出生体重无显著性差异(P>0.05)。<28周组超声异常的孕妇、引产人数、死胎或引产不良结局发生人数明显多于≥28周组(P<0.05)。<28周组的新生儿存活率、新生儿窒息率、剖宫产率低于≥28周组(P<0.05);<28周组的胎盘体积小于≥28周组(P<0.05)。结论 FGR需早发现、早诊断及早治疗,尽可能延长孕周,适时终止妊娠,以改善新生儿结局。

Objective To explore the etiology, monitoring, treatment and pregnancy outcome of fetal growth restriction （FGR）. Methods From July 2014 to July 2017, the clinical data of 61 pregnant women with single FGR were collected in our hospital. According to the discovery of FGR gestational weeks, they were divided into 〈28 weeks group and 〈28 weeks group. The clinical data of the two groups were retrospectively analyzed. Results There were no significant differences in age, parity, presence or absence of comorbidities, abnormality of placenta umbilical cord, number of treatment, treatment efficiency, number of vaginal delivery, birth weight of newborns between the two groups （P〉0.05）. The pregnant women with ultrasound abnormalities, induced labor, number of stillbirth or induction of labor in the 〈28 weeks group were significantly more than those in the 〈28 weeks group （P〈0.05）. The placental volume, cesarean sections rate, newborns survived rate and neonatal asphyxia rate in the 〈28 weeks group were significantly less than those in the 〈28 weeks group （P〈0.05）. Conclusion FGR needs early detection, early diagnosis, early treatment, the extension of gestational age as much as possible, timely termination of pregnancy in order to improve the outcome of the newborn.