阴道3D-CPA诊断绝经后子宫内膜良、恶性病变的准确性研究

Diagnostic value of vaginal three-dimensional Doppler ultrasonography in endometrial disease

目的探讨阴道三维彩色能量多普勒超声(3D-CPA)诊断绝经后妇女子宫内膜疾病的准确性和对内镜电切术的指导价值。方法选取110例绝经后患有子宫内膜疾病患者为研究对象。根据患者病理组织学检验结果,分为子宫内膜病变良性组和恶性组。分析阴道3D-CPA诊断绝经后子宫内膜疾病的准确性。结果恶性组各项超声参数、血流参数及微血管密度(MVD)值与良性组比较,差异有统计学意义(P<0.05);不同分期患者的各项超声参数差异无统计学意义(P>0.05),但晚期患者的MVD数值高于Ⅰ期与Ⅱ期患者,且Ⅱ期患者高于Ⅰ期(P<0.05);阴道3D-CPA的特异性和敏感性值均相对较高。结论阴道3DCPA鉴别绝经后子宫内膜疾病临床诊断效果好,对内镜电切术的治疗具有临床指导价值。

Objective To investigate the diagnostic accuracy of vaginal three-dimensional Doppler ultrasonography（3 D-CPA） in endometrial disease of female patients in postmenopausal state. Methods A total of 110 patients with endometriosis were selected in this study. Patients were divided into 2 groups based on histopathological examination： benign group and malignant group. 3 D-CPA was performed in each case. Results The ultrasonographic parameters, blood flow parameters and microvessel density（MVD） in malignant group were significantly different from those in the benign group（P〈0.05）. No significant difference in the ultrasonographic parameters among various stages was founded（P〉0.05）. MVD of patients with advanced stage was significantly increased compared with inferior stage. 3 D-CPA results suggested that it could specifically recognize patients with malignant patients. Conclusion 3 D-CPA is worthy for clinical application in screening patients with malignant endometrial disease with high specificity and sensitivity.