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多模式镇痛对下肢骨折患者术后疼痛 炎性因子及免疫功能的影响 被引量:7

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摘要 目的探讨多模式镇痛(MMA)对下肢骨折患者术后疼痛、炎性因子及免疫功能的影响。方法选取我院2016年6月—2017年3月收治的72例下肢骨折患者,按照入院先后顺序将其分成观察组与对照组。对照组单纯使用芬太尼PCIA镇痛,观察组采用多模式镇痛。对比2组视觉模拟评分法(VAS)评分、白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)水平及外周血CD4^+/CD8^+比例。结果观察组术后12 h、24 h的VAS评分明显低于对照组(P<0.05);观察组术后24 h、72 h的IL-6、TNF-α水平低于对照组差异均有统计学意义(P<0.05);观察组术后24 h、72 h的CD4^+/CD8^+均高于对照组(P<0.05)。结论多模式镇痛可明显缓解下肢骨折患者术后疼痛,改善炎性反应,临床应用价值高。
作者 叶海啸
出处 《基层医学论坛》 2018年第17期2377-2378,共2页 The Medical Forum
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