从2017 ASCO年会看肿瘤代谢及营养支持研究的进展

Progress in 2017 ASCO annual meeting: cancer metabolism and nutrition support

肿瘤是世界范围内居民死亡的最主要原因之一。肿瘤异常的代谢状态及靶向代谢抗肿瘤治疗正成为肿瘤研究领域的热点。值2017年美国临床肿瘤学会(American Society of Clinical Oncology,ASCO)年会闭幕之际,本文就靶向代谢通路药物的临床研究、基于代谢原理的肿瘤显像技术、代谢分子在肿瘤发生发展中的作用和机制、临床营养方案和营养评估等4个方面综述肿瘤代谢及营养支持研究的进展。

Cancer is one of the leading causes responsible for resident＇s death worldwide. The abnormal status of cancer metabolism and metabolic target antitumor therapy are becoming the hotpot in cancer research. Shortly after the close of 2017 American Society of Clinical Oncology（ASCO） annual meeting,the progress in the field of cancer metabolism and nutrition support could be reviewed in four aspects： clinical investigation of drugs targeting metabolic pathway,metabolism based radiological technologies,role and mechanism of metabolic molecules involved in tumor initiation and progress,and clinical nutrition support.