肿瘤患者医院感染率及危险因素调查分析

Investigation on incidence and risk factors for hospital acquired infection in patients with cancer

目的了解住院肿瘤患者医院感染的特点及相关危险因素,为制定防控措施提供科学理论依据。方法通过回顾性调查方法,对某医院住院肿瘤患者医院感染情况及其危险因素进行调查与分析。结果共调查该医院住院肿瘤患者695例,发生医院感染22例,感染率为3.17%;感染部位以下呼吸道为主。从感染患者送检标本中分离病原菌26株,以革兰阴性菌为主。logistic回归分析结果显示,低血清白蛋白、低白细胞及住院时间等因素为肿瘤患者发生医院感染的独立危险因素。结论住院肿瘤患者医院感染危险因素明确,应制定有针对性的防控干预措施。

Objective To explore the characteristics and risk factors for hospital acquired infection（ HAI） in patients with cancer,so as to provide scientific theoretical basis to prevent the occurrence of HAI. Methods Retrospective investigation was used to survey and analyze infection status and risk factors for hospital acquired infection（ HAI） in patients with cancer. Results Of the 695 patients with cancer,22 cases（ 3. 17%） had HAI,the main infection site was inferior respiratory tract. 26 strains of pathogens were isolated,most was Gram-negative bacterium. Logistic analysis suggested that low serum albumin level,low white blood cell count and length of stay were independent influence factors of HAI in patients with cancer. Conclusion The incidence of HAI in patients with cancer is high,and the risk factors were clear. Intervention measures aiming at the corresponding risk factors should be made.