玛咖片缓解小鼠体力性疲劳作用的实验研究

Effect of Maca Tablets on Alleviating Physical Fatigue in Rats

目的研究玛咖片缓解体力疲劳的作用。方法将小鼠按体重随机分为高、中、低三个剂量组和对照组,高、中、低剂量组分别灌胃给予2400、800、400mg/(kg·d)的玛咖片30d,对照组给予纯净水。通过小鼠负重游泳实验,测定玛咖片对小鼠负重游泳时间、血清尿素氮含量、肝糖原含量、血乳酸浓度的变化。观察小鼠运动性疲劳时玛咖片对体内相关指标的影响。结果各剂量组小鼠负重游泳时间均比对照组延长;低、中剂量组小鼠肝糖原含量均比对照组增加;各剂量组小鼠尿素氮含量及小鼠游泳后血乳酸曲线下面积均小于对照组。结论玛咖片具有一定的缓解体力性疲劳的作用。

OBJECTIVE To study the alleviating physical fatigue in rats of Maca tablets. METHODS The mice were selected and divided into 4 groups： high-dose group,middle-dose group,low-dose group were fed with2400 mg/（ kg·d）,800 mg/（ kg·d）,400 mg/（ kg·d） of Maca tablets respectively,and blank control group was fed with water for 30 d. The time of weight loading swimming,blood urea nitrogen,the level of liver glycogen and blood lactic acid after the exercise in the mice were detected. The change of the relative indexes in vivo was observed after Maca tablets used when the mice were in fatigue. RESULTS The swimming time insisted in the loaded swimming test in Maca tablets groups was higher than in the control group; the concent of liver glycogen in the low-dose group and middle-dose group was raised and higher than the control group; the concent of blood urea nitrogen and lactic acid in the Maca tablets groups was dropped and lower than the control group. CONCLUSION There is an effect of Maca tablets on alleviating physical fatigue.