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开胸术后重症肺炎鲍曼不动杆菌的检测及耐药性分析 被引量:2

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摘要 目的探究在治疗重症肺炎开胸术后运用传统培养法与实时荧光定量PCR法检测患者感染鲍曼不动杆菌的情况,为临床用药作出正确指导。方法选取惠州地区最大的三甲综合医院2014年8月—2017年8月被确定为开胸术后重症肺炎患者124例,将其分为2组,各62例。对照组采用传统培养检测及药敏试验法,观察组采用实时荧光PCR的检测及耐药基因测定方法,观察对比2组患者感染鲍曼不动杆菌检出率、药敏试验情况、住院情况及费用。结果观察组对患者感染鲍曼不动杆菌的检测时间比对照组短,检出率比对照组高,差异有统计学意义(P<0.05)。观察组与对照组耐药性差异有统计学意义(P<0.05)。在常规治疗与指导用药治疗后,观察组住院时间及费用低于对照组(P<0.05)。结论运用实时荧光定量PCR方法检测鲍曼不动杆菌的检出率比传统培养法高,检测患者感染鲍曼不动杆菌耐药性比半自动细菌分析仪时效快,具有临床实用性。经耐药性试验后指导临床合理用药的患者住院时间短,费用较低,可有效减轻患者经济负担。
出处 《中国校医》 2018年第6期453-454,共2页 Chinese Journal of School Doctor
基金 惠州市科技项目(2016Y091)
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