郑氏大力丸制备工艺及质量标准研究

Preparation process and quality standard of Zheng's Dali pills

目的:研究郑氏大力丸的制备工艺和质量标准中药物的薄层鉴别方法。方法:从丸剂自动化生产角度考察郑氏大力丸生产工艺的可行性,并建立熟地黄和人参专属性强、简便的薄层鉴别方法。结果:郑氏大力丸的生产工艺为:在出条口直径5mm,推料速度与切丸速度500r/min的条件下,以纯化水为粘合剂制成含水量28.6%的软材后进行制丸;郑氏大力丸中熟地黄、人参薄层鉴别方法重现性良好。结论:郑氏大力丸制备工艺合理、质量标准良好,可以应用于生产。

Objective： To investigate the preparation process for Zheng＇s Dali pills and thin-layer chromatography（TLC） for the identification of traditional Chinese medicines in quality standard. Methods： The feasibility of the preparation process for Zheng＇s Dali pills was investigated from the perspective of automatic production of pills,and a highly specific and convenient TLC method for the identification of prepared Radix Rehmanniae and Panax ginseng was established. Results： The preparation process for Zheng＇s Dali pills was as follows： with an outlet diameter of 5 mm and a speed of pushing and cutting of 500 r/min,soft material with a water content of 28. 6% was made with purified water as an adhesive and then processed into pills. The TLC method for the identification of prepared Radix Rehmanniae and Panax ginseng has good repeatability. Conclusion： The preparation process for Zheng＇s Dali pills is reasonable and has good quality standards,and therefore,it can be used in production.