3Vincent JL, Opal SM, Marshall JC, et al. Sepsis definitions: time for change [J]. Lancet, 2013, 381(9868): 774-775.
4Martin GS, Mannino DM, Moss M. The effect of age on the develop- ment and outcome of adult sepsis [J]. Crit Care Med, 2006, 34(1): 15-21.
5Wenzel RP, Edmond MB. Septic shock - evaluating another failed treatment [J]. N Engl J Med, 2012, 366(22): 2122-2124.
6Hotchkiss RS, Monneret G, Payen D. Immunosuppression in sep- sis: a novel understanding of the disorder and a new therapeutic approach [J]. Lancet Infect Dis, 2013, 13(3): 260-268.
7Ward PA. Immunosuppression in sepsis [J]. JAMA, 2011, 306(23): 2618-2619.
8Hotchkiss RS, Karl IE. The pathophysiology and treatment of sep- sis [J]. N Engl J Med, 2003, 348(2): 138-150.
9Xiao W, Mindrinos MN, Seok J, et al, A genomic storm in critical- ly injured humans [J]. J Exp Med, 2011, 208(13): 2581-2590.
10Boomer JS, To K, Chang KC, et al. Immunosuppression in patients Who die of sepsis and multiple organ failure [J]. JAMA, 2011, 306 (23): 2594-2605.