阿尔兹海默病早期认知功能障碍和高脂血症的相关性分析

Correlation analysis between early cognitive impairment and hyperlipidemia in Alzheimer's disease

目的:探讨阿尔兹海默病早期认知功能障碍患者与高脂血症的相关性。方法:将80例阿尔兹海默病早期认知功能障碍患者分为AD组,100例健康人群分为正常组,检测两组的血清总胆固醇(TC)、低密度脂蛋白(LDL-C)及甘油三酯(TG)。比较各组血脂水平。结果:AD组高脂血症的发生率、总胆固醇(TC)、低密度脂蛋白(LDL-C)、甘油三酯(TG)水平明显高于正常组(P<0.05)。结论:血脂水平与阿尔兹海默病轻度认知功能障碍高度相关。

Objective： To investigate the correlation between early cognitive impairment in patients with Alzheimer＇s disease and hyperlipidemia. Methods： 80 patients with early cognitive impairment of Alzheimer＇s disease were divided into AD group,while 100 healthy people were divided into normal group,and detected their serums total cholesterol（ TC）,low density lipoprotein（ LDL-C） and triglyceride（ TG）. Last,compared the levels of serum lipid between the two group. Results： The incidence of hyperlipidemia,total cholesterol（ TC）,low density lipoprotein（ LDL）,triglyceride（ TG） in the AD group were significantly higher than those in the normal group（ P〈0. 05）. Conclusion： Serum lipid levels were highly correlated with mild cognitive impairment in Alzheimer＇s disease.