亲和人体与非亲和人体双歧杆菌之间的生理特征差异

Physiological difference between the Human-Residential-Bifidobacteria and No-Human-Residential-Bifidobacteria

叙述了不同寄宿起源的双歧杆菌之间的基因型及生理特征的差异,以及有关双歧杆菌的保健功能的最新研究结果,旨在探讨如何选择最佳的益生菌。一般来说,双歧杆菌可根据不同寄宿环境分为两大类:寄宿于人类的菌种为亲和人体双歧杆菌(HumanResidential Bifidobacteria,HRB),而寄宿于动物或其他环境的为非亲和人体双歧杆菌(Non-Human-Residential Bifidobacteria,非HRB)。众多的研究表明HRB菌株将会是更理想的人类益生菌,特别是用于婴幼儿,且对宿主会有更多的功效和更高的安全性。

This review aims to provide an overview of the genotypic and physiological differences of bifidobacteria associated with different residential origins and to shed light on the practical considerations for selection of bifidobacteria as probiotics in order to establish a healthy gut microbial community in humans.Bifidobacteria naturally inhabit a range of ecological niches and display substantial differences in their ecological adaptation among species. In general, bifidobacteria could be categorized into two major groups; bifidobacterial species of human origins as Human-Residential B^dobacteria （HRB） while other species which are the natural inhabitants of animals or environment as non-HRB.Lines of evidence suggest that HRB especially infant-type HRB are more readily to colonize in infant gut and therefore may exert better health-promoting effects to the human host.