加味补中益气汤治疗肥胖型多囊卵巢综合征临床疗效观察

Clinical Observation of Jiawei Buzhong Yiqi Decoction in the Treatment of Obese Polycystic Ovarian Syndrome

目的:观察加味补中益气汤治疗肥胖型多囊卵巢综合征(polycystic ovarian syndrome,PCOS)的临床疗效。方法:纳入2014年9月-2016年12月在我院中医妇科门诊就诊的肥胖型多囊卵巢综合征患者,给予加味补中益气汤服用,每日一剂,连续服用3个月,于治疗前后计算体质指数(body mass index,BMI),检测性激素水平和排卵情况,并比较治疗前后临床症状的改善情况。结果:40例肥胖型PCOS患者经治疗后,BMI、血清黄体生成激素(LH)、睾酮(T)水平较治疗前显著下降,血清雌二醇(E2)水平较治疗前显著升高,卵巢增大及多囊改变、月经周期、经量及经期均有不同程度改善。结论:加味补中益气汤治疗肥胖型PCOS具有较好的临床疗效。

Objective To observe the clinical efficacy of Jiawei Buzhong Yiqi Decoction in the treatment of polycystic ovarian syndrome（ PCOS）.Methods Obese patients with PCOS were recruited for the study from September 2014 to December 2016 at the gynecological clinic in our hospital. All these patients were given one dose of Jiawei Buzhong Yiqi Decoction daily for 3 months. Body mass index（ BMI）,sex hormone levels and ovulation were measured,and the improvement of clinical symptoms before and after treatment was compared.Results After treatment,the levels of BMI and serum luteinizing hormone（ LH）,testosterone（ T） in 40 obese PCOS patients were significantly lower than those before treatment,and the level of serum estradiol（ E2） was significantly higher than that before treatment. Ovarian enlargement and polycystic changes,menstrual cycle,menstrual flow and menstrual period were improved to varying degrees. Conclusion Jiawei Buzhong Yiqi Decoction has a good clinical efficacy in the treatment of obese PCOS.