复方小儿退热栓治疗小儿高热惊厥45例

Randomized Comparative Study of Infantile Febrile Convulsion by Compound Children's Antipyretic Suppository with Acetaminophen Suspension Drops

目的:观察复方小儿退热栓治疗小儿高热惊厥的临床疗效。方法:将90例高热惊厥患儿随机分为观察组和对照组,每组各45例。对照组患儿给予对乙酰氨基酚混悬滴剂治疗,观察组患儿给予复方小儿退热栓治疗。比较两组患儿的临床疗效、中医证候疗效、康复情况、治疗期间不良反应情况以及治疗前后中医证候积分、脑电图异常、心肌酶异常及免疫功能异常改善情况。结果:临床疗效:对照组有效率为75.56%,观察组有效率为91.11%,两组患儿临床疗效比较,差异具有统计学意义(P<0.05)。中医证候疗效:观察组有效率为93.33%,高于对照组的77.78%,两组患儿中医证候疗效比较,差异具有统计学意义(P<0.05)。观察组治疗后中医证候积分低于对照组,差异具有统计学意义(P<0.05)。观察组治疗后惊厥发生次数、惊厥好转时间、高热消退时间以及住院时间低于对照组,差异具有统计学意义(P<0.05)。观察组治疗后脑电图异常率、心肌酶异常率及免疫功能异常率低于对照组,差异具有统计学意义(P<0.05)。观察组不良反应发生率低于对照组,差异具有统计学意义(P<0.05)。结论:复方小儿退热栓治疗小儿高热惊厥疗效显著,可有效改善患者临床症状,缩短康复时间,且不良反应少。

Objective To compare the clinical effect of infantile febrile convulsion by Compound children＇ s antipyretic suppository with Acetaminophen suspension drops. Methods 90 cases of infantile febrile convulsion were rando m Ly divided into observation group（45 cases） and control group（45 cases）. The control group were treated by Acetaminophen suspension drops. The observation group were treated by Compound children＇ s antipyretic suppository. The clinical effect were observed. Results The clinical effect and chinese medicine certificate waits curative effect of the observation group were better than the control group（ P〈0. 05）;The score of Chinese medical syndrome for the observation group after treatment were lower than the control group（ P〈0. 05）;The frequency of convulsions,convulsions improve time,high fever subsided and hospital stays for the observation group were lower than the control group（ P〈0. 05）;The rate of encephlogram anomaly,myocardial enzyme anomaly and immunologic function anomaly for the observation group after treatment were lower than the control group（ P〈0. 05）;The rate of total untoward effect for the observation group were lower than the control group（ P〈0. 05）. Conclusion It has prominent effect in infantile febrile convulsion by compound children＇s antipyretic suppository. It can improve the clinical symptoms,rehabilitation and untoward effect. It worth of clinical recommendations.