慢性阻塞性肺疾病中医证型与预后相关性分析

Study on Correlation between TCM Syndrome and Prognosis of Chronic Obstructive Pulmonary Disease in Stable Stage

目的：探讨慢性阻塞性肺疾病（COPD）稳定期中医证型与预后的关系。方法：将符合纳入标准的121例患者分为肺气虚、肺脾气虚、肺肾气虚3组,临床随防1年圣乔治呼吸问卷（SGRQ）评分、肺功能、急性加重次数,整理相关数据进行统计学分析,以P〈0.05为差异有统计学意义。结果：在各随访时间点,SGRQ评分及急性发作次数按肺气虚、肺脾气虚、肺肾气虚升高;而肺功能按肺气虚、肺脾气虚、肺肾气虚的顺序下降,差异分别有统计学意义（P〈0.05）。结论：COPD患者中医证型与预后之间有相关性。

Objective：The purpose of this study was to evaluate the correlation between TCM syndrome type and the prognosis of patients. Methods：All the 121 patients of COPD in stable stage were divided into three groups according to TCM syndrome types：Qi deficiency of lung group,Qi deficiency of lung and spleen group and Qi deficiency of lung and kidney group. They were carried out followed-up visits study for one year. St.Georges respiratory questionnaire（SGRQ）,pulmonary function,also the exacerbation numbers were recorded. Collated data for statistical analysis,P〈0.05 for the difference was statistically significant. Results：During the period of followed-up visits,the SGRQ scores and exacerbation numbers were increased and arranged in the order of Qi deficiency of lung group,Qi deficiency of lung and spleen group,Qi deficiency of lung and kidney group;lung function were decreased and arranged in the order of Qi deficiency of lung group,Qi deficiency of lung and spleen group,Qi deficiency of lung and kidney group. All the difference was statistically significant（P〈0.05）. Conclusion：There was good correlation between TCM type and the prognosis of patients