制药专业药物合成实践课程项目化教学探索

Exploration of Project-Oriented Laboratory Curriculum for Pharmaceutical-Majored Students

根据制药专业药物合成类课程特点，详述了以美国IUPUI大学国际化教科研项目“分散式药物发现”计划为蓝本的“药物的合成设计与制备实验”课程项目化教学改革在我校制药类专业实践教学中的应用。通过对该课程进行连续2年的跟踪探索，发现这种教学模式不但可以使学生充分了解当今国际药物开发的前沿技术，开阔了眼界，也培养了学生主动学习和思考的动力与能力，提高了他们的创新意识、科学精神及团队协作意识，为今后的职业发展打下坚实基础。

In this paper, the dilemma that both reformed project-oriented curriculum and old ones co-existing has been analyzed, and this problem may be solved by the introduction and execution of project-oriented curriculum. In practice, a global undergraduate teaching-research pro- gram ＂distributed drug discovery （D3）＂ developed by teaching fellows in the Department of Chemistry and Chemical Biology at Indiana University-Purdue University Indianapolis （IUPUI） has been incorporated into pharmaceutical-majored student laboratory curriculum at Zhejiang Pharmaceutical College. After continuous two-year follow-up investigation, it has been found that this type of laboratory curriculum is able to get students involved in the most advanced research project. As a result, students acquired good sense of achievement in the laboratory skills while their horizons for cutting edge technology in drug discovery have been broadened. More importantly, their motivation for learning and reasoning, the sense of innovation, scientific spirit, and their effort for team-work were greatly improved, which, in turn, will significantly benefit their career development. Therefore, the project-oriented curriculum which is well matched with the characteristies of the students is becoming an inexorable trend for the education reform of higher vocational colleges.