摘要
分子靶向治疗药物使恶性肿瘤的治疗进入一个新的时代,但相关的不良反应严重影响患者生活质量,导致靶向治疗药物减量或中断,降低抗肿瘤疗效。采用中医药防治靶向药物相关皮疹、手足皮肤反应、腹泻、周围神经病变等,取得了良好的疗效。检索中国期刊全文数据库、万方数据库及Pubmed中关于中药干预靶向药物相关不良反应的临床研究报道,并进行系统综述。
Target agents provide new treatment for malignant tumors. However,target agents related adverse events( AEs) can have a negative impact on the patient's quality of life( QOL),leading to dose modifications or drug discontinuation and compromising clinical outcome. Traditional Chinese Medicine( TCM) produced a benefit in prevention and treatment of these AEs. Clinical studies were identified by literature searches in China National Knowledge Infrastructure( CNKI) database,Wan-Fang Database and Pub Med database and a systematic review of TCM for target agents related AEs was produced.
作者
邓博
贾立群
邓超
张亚男
刘青
DENG Bo;JIA Liqun;DENG Chao;ZHANG Yanan;LIU Qing(Integrative Oncology Department, China- Japan Friendship Hospital, Beijing 100029, China;Beijing University of Chinese Medicine, Beijing 100029,China)
出处
《中华中医药学刊》
CAS
北大核心
2018年第7期1580-1583,共4页
Chinese Archives of Traditional Chinese Medicine
基金
国家自然科学基金项目(81603462)
首都卫生发展科研专项项目(首发2018-2-40610)
中日友好医院院级项目(2016-1-QN-6,2016-2-QN-16)
关键词
靶向治疗药物
不良反应
中药
target agents
adverse events
traditional Chinese medicine