支气管肺泡灌洗术对儿童重症肺炎的临床疗效分析

Bronchoalveolar Lavage for Severe Pneumonia in Children

目的:为采用支气管肺泡灌洗术治疗儿童重症肺炎提供基础研究参考资料。方法:选取2014年9月至2017年9月在我院就诊的重症肺炎患儿67例,根据治疗方法不同分为研究组(采用常规治疗方法+支气管肺泡灌洗术)34例和对照组(采用常规治疗方法)33例,检测患儿血清白细胞、C反应蛋白和降钙素水平,评价治疗效果并比较两组患儿的预后及并发症发生情况。结果:研究组患儿治愈率和总有效率分别为52.94%和91.18%,均高于对照组的24.24%和66.67%(P均<0.05);住院时间、咳嗽消失时间、抗生素使用时间、啰音消失时间、胸部X线片阴影消退时间、发热时间均短于对照组(P均<0.05)。治疗后两组患儿血清白细胞、C反应蛋白和降钙素水平均较治疗前下降,且研究组均低于对照组(P均<0.05)。两组患儿发生发热、一过性低氧血症、咳嗽加重的比例比较差异均无统计学意义(P均>0.05),但研究组患儿发生呼吸急促的比例低于对照组(P<0.05)。结论:支气管肺泡灌洗术对儿童重症肺炎具有良好的治疗效果,且并发症较少。

Objective： To provide basic research references for bronchoalveolar lavage for severe pneumonia in children. Methods：Sixty-seven children with severe pneumonia admitted into Sept. 2014 to Sept. 2017 were extracted to be divided into research group（ conventional treatment ＋ bronchoalveolar lavage） with 34 cases and control group（ conventional treatment） with 33 cases. Serum leukocytes,C-reactive protein and calcitonin levels were detected,therapeutic effects were evaluated,prognosis and complications of two groups were compared. Results： The cure rate and total efficiency of research group were 52. 94% and 91. 18% respectively,higher than those of control group 24. 24% and 66. 67%（ P 〈0. 05）. The length of stay,disappearance time of cough,application time of antibiotics,disappearance time of rales,disappearance time of chest X-ray shadow and time of fever of research group were all shorter than those of control group（ P 〈0. 05）. After treatment,the serum leukocytes,C-reactive protein and calcitonin levels of both groups were decreased compared with before treatment,and the research group was lower than the control group（ P 〈0. 05）. There was no statistically significant difference in the incidence of fever,transient hypoxemia,and worsening of cough in two groups（ P〉0. 05）,yet the rate of tachypnea in research group was lower than that in control group（ P 〈0. 05）. Conclusion： Bronchoalveolar lavage has significant therapeutic effects in children with severe pneumonia with fewer complications.