慢性鼻窦炎合并哮喘患者CT Lund-Mackay评分与VAS评分相关性分析

Study on correlation between CT Lund-Mackay score and visual analogue scale in chronic sinusitis patients with asthma

目的探讨慢性鼻窦炎合并哮喘患者术前CT Lund-Mackay评分与术前及术后1年主观症状VAS评分的相关性。方法回顾性分析19例慢性鼻窦炎合并哮喘患者术前CT Lund-Mackay评分和主观症状VAS评分及术后1年主观症状VAS评分,采用线性回归分析及配对t检验进行统计学分析。结果患者术前CT LundMackay评分中筛窦、窦口鼻道复合体、上颌窦评分较高,蝶窦最低。患者术前鼻塞、流涕VAS评分较高,头痛及嗅觉减退VAS评分较低。术后1年鼻塞、流涕VAS评分变化较大,头痛次之,嗅觉减退VAS评分变化相对较小(P<0.05)。术前VAS评分(总分)及术后1年VAS评分(总分)与患者术前CT Lund-Mackay评分呈正相关(r=0.465,P=0.045;r=0.522,P=0.022)。结论鼻塞、流涕是术前慢性鼻窦炎合并哮喘患者的主要鼻部症状,术后鼻塞、流涕、头痛、嗅觉减退均有改善,其中鼻塞、流涕改善最明显。术前VAS评分(总分)及术后1年VAS评分(总分)与术前患者CT Lund-Mackay评分相关性良好。对于慢性鼻窦炎合并哮喘患者术前进行鼻窦CT客观评估,对于手术效果评估具有重要意义。

ObjectiveTo investigate the correlation between the preoperative CT Lund-Mackay score and pre- and/or postoperative visual analogue scale （VAS） of subjective symptom in chronic sinusitis patients with asthma.MethodsThe preoperative CT Lund-Mackay scores and pre-and/or postoperative visual analogue scales （VAS） of subjective symptoms in 19 chronic sinusitis patients with asthma were analyzed retrospectively. Linear regression analysis and paired t-test were adopted to explore the results.ResultsThe preoperative CT Lund-Mackay scores of ethmoidal sinus, ostiomeatal complex, frontal sinus were relatively high, and that of sphenoid sinus was the lowest. Before operation, the VAS of nasal obstruction and rhinorrhoea were relatively high and those of headache and dysosmia were relatively low. One year after operation, the scales changed greatly in nasal obstruction and rhinorrhea, and slightly in headache and dysosmia （all P〈0.05）. The preoperative CT Lund-Mackay scores were positively correlated with VAS of the subjective symptoms both before and after operation （r=0.465,P=0.045; r=0.522,P=0.022 respectively）.ConclusionNasal obstruction and rhinorrhoea are the primary nasal symptoms in chronic sinusitis with asthma. Surgical treatment can improve such symptoms as nasal obstruction, rhinorrhoea, headache and dysosmia, especially the former two. The preoperative CT Lund-Mackay scores are well correlated with VAS of the subjective symptoms both before and after operation. It is important for chronic sinusitis patients with asthma to perform sinus CT scanning in evaluating the surgical outcomes.