FDP、D-二聚体在恶性肿瘤血瘀证腹水患者预后中的意义

Effect of the FDP and D-dimer on the Prognosis of the Malignant Tumor Patients with Ascites Combined Blood Stasis Syndrome

目的:探讨FDP、D-二聚体在血瘀证且合并腹水形成的恶性肿瘤患者预后中意义。方法:选择存在血瘀证表现的腹水组患者14名,无腹水组患者17名,比较2组肿瘤患者凝血功能中凝血酶原时间(PT)、凝血酶时间(TT)、部分活化凝血酶原时间(APTT)、纤维蛋白原(FIB)、纤维蛋白原降解产物(FDP)及D-二聚体水平的差别。结果:2组患者在PT、TT、APTT、FIB方面无明显差别(P>0.05),有腹水形成肿瘤患者的FDP、D-二聚体水平高于无腹水形成的肿瘤患者(P<0.05)。结论:FDP、D-二聚体的升高可能提示有腹水形成的肿瘤患者血液更加高凝,对预后评估具有一定意义。

Objective： To study the effect of the FDP, D-dimer on the prognosis of the malignant tumor patients with blood stasis syndrome and ascites. Methods： 14 patients with ascites group and 17 patients with no ascites group which all combined blood stasis syndrome were studied. The difference in prothrombin time（PT）, thrombin time（TT）,partial activated prothrombin time（APTT）, fibrinogen（FIB）, fibrinogen degradation products（FDP）and D-dimer were compared between the two groups patients. Results： The PT, TT, APTT, FIB had no significant difference between two groups（P〉0.05）. The levels of FDP and D-dimer in ascites group were higher than that in no ascites groups（P〈0.05）.Conclusion： The higher of FDP and D-dimer may promt the higher blood coagulation condition in the ascites group. It has the certain significance in the evaluation of prognosis.