摘要
目的探讨严重Pierre Robin综合征患儿围手术期的监护特点。方法回顾分析2013年3月至2015年1月间我科收治的48例严重Pierre Robin综合征患儿围手术期临床资料,对其临床治疗进行总结分析。结果48例患儿均治愈出院,无死亡病例;患儿术后机械通气时间为(2.76±3.58)d,入科与出科时血气分析比较[pH值:7.33±0.07比7.44±0.08,PaCO2:(49.12±15.63) mmHg比(36.19±8.13) mmHg,PaO2:(74.28±17.09) mmHg比(114.00±53.55) mmHg],差异均有统计学意义(P均〈0.05);出科时前白蛋白、视黄醇结合蛋白水平较入科时明显升高[前白蛋白:(0.10±0.04) g/L比(0.14±0.05) g/L,视黄醇结合蛋白:(19.85±9.76) mg/L比(25.15±8.72)mg/L],差异均有统计学意义(P均〈0.05)。结论呼吸机治疗及营养支持是严重Pierre Robin综合征患儿围手术期重要的治疗措施,能够取得较满意的疗效。
ObjectiveTo study perioperative monitoring characteristics of severe Pierre Robin syndrome in children.MethodsThe clinical data of 48 infants with Pierre Robin syndrome admitted to the department of surgical intensive care unit from March 2013 to January 2015 were retrospectively reviewed.ResultsAll 48 cases were cured and discharged without death.The average duration of mechanical ventilation after the operation was(2.76±3.58)days.There were significant differences in blood gas analysis before and after treatment in surgical intensive care unit(pH: 7.33±0.07 vs. 7.44±0.08, PaCO2: (49.12±15.63)mmHg vs.(36.19±8.13) mmHg, PaO2: (74.28±17.09) vs.(114.00±53.55) mmHg)(P〈0.05, respectively). The levels of prealbumin and retinol binding protein increased significantly after treatment[prealbumin: (0.10±0.04)g/L vs.(0.14±0.05) g/L, retinol binding protein: (19.85±9.76)mg/L vs.(25.15±8.72)m g/L](P〈0.05, respectively).ConclusionReasonable mechanical ventilation combined with available nourishments support could help to improve the prognosis of severe Pierre Robin syndrome.
作者
张明
陆巍峰
Zhang Ming;Lu Weifeng(Department of Surgical Intensive Care Unit, Children′s Hospital affiliated to Nanjing Medical University, Nanjing 210008, China)
出处
《中国小儿急救医学》
CAS
2018年第6期471-474,共4页
Chinese Pediatric Emergency Medicine