转化糖电解质注射液对腹腔镜胃肠道手术患者围术期血糖的影响

Effect of invert sugar injection on blood glucose in patients undergoing laparoscopic surgery

目的:探讨腹腔镜胃肠道手术患者术中输注转化糖电解质注射液(ISI)对患者围术期血糖及电解质的影响。方法:选择在广西医科大学第二附属医院普通外科行腹腔镜阑尾切除术、腹腔镜疝气修补术的非糖尿病患者45例,按随机数字表法分为3组,每组15例,A组使用乳酸钠林格氏液,B组使用复方电解质MG3含糖液,C组使用ISI。观察并记录3组患者气腹前(T0)、气腹后30min(T1)、气腹后60min(T2)、拔除气管导管后15min(T3)4个时点的血糖值、动脉血电解质值。结果:与A组比较,B组、C组患者血糖值在T1、T2时间点升高(P<0.05),但同时间点C组血糖值均低于B组(均P<0.05);3组在各时间点的电解质值比较,差异均无统计学意义(均P>0.05)。结论:腹腔镜术中用ISI代替复方电解质MG3含糖液可避免患者血糖波动,且不会造成电解质紊乱,有利于患者内环境的稳定。

Objective：To investigate the effect of invert sugar injection（ISI）on blood glucose and electrolytes in patients undergoing laparoscopic surgery.Methods：45 patients with non-diabetes mellitus who underwent laparoscopic appendectomy and laparoscopic hernia repair surgery in our hospital were selected,and randomly divided into three groups（n=15 per group）：group A in which the patients received lactated Ringer＇s solution,group B in which the patients received compound electrolytes and glucose injection MG3,group C in which the patients received ISI.The levels of blood glucose and electrolyte were recorded before pneumoperitoneum（T0）,30 min after pneumoperitoneum（T1）,60 min after pneumoperitoneum（T2）,and 15 min after extubation（T3）.Results：Compared with group A,blood glucose was increased in group B and C at T1 and T2（P〈0.05）,and was lower in group C than that in group B（P〈0.05）.No significant difference was found in electrolyte level among the three groups at each time point（P〉0.05）.Conclusion：ISI used instead of compound electrolytes and glucose injection MG3 during laparoscopic surgery could regulate blood glucose level and water-electrolyte balance,thus maintain a stable internal environment of patients.