摘要
Objective:To investigate the prevalence of metabolically healthy obesity(MHO)and its relationship with incidence of metabolic syndrome(MetS),type 2diabetes mellitus(T2DM)and hypertension in individuals in the city of Yulin.Methods:We studied 1,666 participants,aged over18years at baseline,with free of components of the MetS except waist criteria.Participants were divided into three groups based on body mass index(Ibm):lean/normal weight(Ibm<23kg/m2),overweight(Ibm,23-24.9kg/m2),obesity(Ibm≥25 kg/m2).The cumulative incidence of MetS,T2DM and hypertension over 5.21years among groups was assessed.Results:The prevalence of MHO was 19.5%in the baseline population.During an average 5.21year follow-up,the cumulative incidence of MetS,T2DM and hypertension in1,666participants were 16.4%,19.1%and 3.9%,respectively.The obesity group had a significantly higher cumulative incidence of MetS(16.4%vs.3.2%,P<0.001),hypertension(19.1%vs.3.7%,P<0.001),and T2DM(3.9%vs.1.6%,P<0.001)compared to the lean/normal weight group.Each kg/m2 of Ibm carried increased risk for T2DM(19%),hypertension(11%)and MetS(13%).Conclusion:Metabolically healthy obesity individuals confer increased risk for hypertension,T2DM and the MetS than their non-obese counterparts.
Objective：To investigate the prevalence of metabolically healthy obesity（MHO）and its relationship with incidence of metabolic syndrome（MetS）,type 2 diabetes mellitus（T2 DM）and hypertension in individuals in the city of Yulin.Methods：We studied 1,666 participants,aged over18 years at baseline,with free of components of the MetS except waist criteria.Participants were divided into three groups based on body mass index（Ibm）：lean/normal weight（Ibm23 kg/m2）,overweight（Ibm,23-24.9 kg/m2）,obesity（Ibm ≥25 kg/m2）.The cumulative incidence of MetS,T2 DM and hypertension over 5.21 years among groups was assessed.Results：The prevalence of MHO was 19.5% in the baseline population.During an average 5.21 year follow-up,the cumulative incidence of MetS,T2 DM and hypertension in1,666 participants were 16.4%,19.1% and 3.9%,respectively.The obesity group had a significantly higher cumulative incidence of MetS（16.4%vs.3.2%,P〈0.001）,hypertension（19.1%vs.3.7%,P〈0.001）,and T2 DM（3.9%vs.1.6%,P〈0.001）compared to the lean/normal weight group.Each kg/m2 of Ibm carried increased risk for T2 DM（19%）,hypertension（11%）and MetS（13%）.Conclusion：Metabolically healthy obesity individuals confer increased risk for hypertension,T2 DM and the MetS than their non-obese counterparts.
出处
《广西医科大学学报》
CAS
2018年第6期794-799,共6页
Journal of Guangxi Medical University
基金
supported by the National Natural Science Foundation of China(No.30660203)
the National Science and Technology Major Project(No.2013ZX10002009)
the Key laboratory of High-Incidence Tumor Prevention (Guangxi Medical University),Ministry of Education(No.GK2015-ZZ06)
关键词
医疗卫生行业
治疗方法
临床分析
理论分析
metabolically healthy obesity
metabolic syndromc
hypertension
type 2 diabetes mellitus
