肠道菌群与溃疡性结肠炎的研究进展

Research progress of intestinal flora and ulcerative colitis

溃疡性结肠炎(UC)是一种以腹痛、腹泻、黏液血便等为主要特征的疾病,随着近年来UC在我国发病率的不断升高,对其研究也越来越受到重视,其中肠道微生态与UC发病机制的联系更是研究重点,本文就UC患者肠道菌群分布、潜在致病菌、肠道菌群与各项指标相关性、益生菌治疗及菌群移植等方面的研究现状进行了阐述。

Ulcerative colitis（UC） is a serious chronic inflammatory disease characterized by recurrent episodes of intestinal ulcer, diarrhea, bloody stools and abdominal pain. In recent years, the incidence of UC has been increasing in our country, and the study on it is now getting more and more attention, with a focus on UC and intestinal flora. In this paper, we will discuss the distribution of intestinal flora, potential pathogenic bacteria, correlation between intestinal flora and indexes, probiotic therapy, and flora transplantation in patients with UC.