青枯雷尔氏菌Ⅲ型分泌蛋白致病侵染的生物信息学初步分析

Bioinformatics Analysis of Pathogenic Infection of Ralstonia Solanacearum on Type Ⅲ Secreted Proteins

以青枯雷尔氏菌为病原菌引起的植物青枯病,是世界性的严重病害。以青枯雷尔氏菌蛋白质组为材料,用EffectiveDB等分析工具对青枯雷尔氏菌的Ⅲ型分泌蛋白进行预测和分析,发现Ⅲ型分泌蛋白主要涉及底物转运、致病侵染以及鞭毛合成等方面。这些蛋白质可能参与了青枯雷尔氏菌对宿主植物的侵染,是两者分子互作的关键参与者。

Plant bacterial wilt disease is one of the diseases most widely distributed and seriously harmful to plants, which is caused by Ralstonia solanacearum. We regard the proteome of Ralstonia solanacearum as basic materials, use Effective DB and other bioinformatic tools to predict and analyse the type Ⅲ secreted proteins of Ralstonia Solanacearum, which could help us comprehend the molecular mechanism of the pathogenic infection. the type Ⅲ secreted proteins are related to the aspects such as transportation of substrates, pathogenic infection and flagella synthesis. These secreted proteins may be involved in the host plant infection process and are key participants of the molecular dialogue.