血清降钙素原对严重多发伤并发感染的预测价值

Predictive value of serum procalcitonin on severe multiple trauma complicated with infection

目的探讨血清降钙素原(PCT)对严重多发伤并发感染的预测价值。方法收集2013年1月-12月95例严重多发伤患者资料进行回顾性分析,根据是否并发感染分为未感染组(42例)和感染组(53例)。比较2组患者的血清PCT水平,分析其差异,探讨其对严重多发伤并发感染的预测价值。结果感染组血清PCT水平高于非感染组血清PCT水平,差异有统计学意义(P<0.01)。用受试者工作特征曲线(ROC)分析显示,血清PCT水平在0.37 ng/ml时,曲线下面积为0.97,灵敏度为94.3%,特异度为90.7%,约登指数为0.85。结论血清PCT对严重多发伤并发感染的预测价值较高,可用于指导临床诊治。

Objective To evaluate the prediction value of serum procalcitonin（ PCT） on severe multiple injuries and infection.Methods A retrospective analysis was performed on 95 patients with severe multiple trauma collected from January 2013 to December 2013,who were divided into the infected group（ 42 cases） and the uninfected group（ 53 cases）. The PCT levels of the two groups were compared for analysis,so as to discuss the prediction value to the severe multiple trauma combined with infections. Results The PCT level of infected group was higher than that of the uninfected group,with the difference statistically significant（ P〈0. 01）. The receiver operating characteristic curve indicated that with the threshold PCT level of 0. 37 ng/ml,the area under the curve was 0. 97,the sensitivity was 94. 3%,the specificity was 90. 7%,and the Youden index was 0. 85.Conclusion Serum PCT level can be used for the prediction of severe multiple injuries complicated with infection,which is capable in clinic.