日光温室从业人员氡暴露与氧化损伤效应关系

Relationship between radon exposure and oxidative damage in solar greenhouse workers

目的探讨日光温室从业人员氡暴露与氧化损伤效应之间的关系。方法采用整群随机抽样方法,以216名日光温室从业人员为研究对象,采用连续测氡仪对日光温室内氡浓度进行现场检测,估算日光温室从业人员氡年均辐射剂量。采集研究对象清晨空腹肘静脉血进行总超氧化物歧化酶(T-SOD)和丙二醛水平检测,对日光温室从业人员氡暴露和氧化损伤效应关系进行探讨。结果 2014年日光温室从业人员接触的氡年均辐射剂量为2.00mSv;T-SOD活力为(87.43±15.77)×10~3U/L,丙二醛水平为(4.36±0.62)μmol/L。多因素Logistic回归分析结果显示,在排除性别、年龄、吸烟、饮酒、种植年限、农药接触评分等混杂因素的影响后,氡暴露剂量越高,T-SOD活力和丙二醛水平发生异常的风险越高(P<0.05)。结论日光温室从业人员日光温室氡暴露与氧化损伤效应之间存在关联性。

Objective To understand the relationship between radon exposure and oxidative damage in solar greenhouse employees.Methods A total of 216 solar greenhouse employees were selected as the study subjects by using cluster random sampling method.Radon concentrations in solar greenhouses were detected by using continuous radon measuring instrument,which were used to estimate the annual radon radiation dose in solar greenhouse employees.T-superoxide dismutase（ T-SOD） and malondialdehyde（ MDA） levels in venous blood were measured,which were used to present the oxidative damage effects in solar greenhouse employees.Results The annual radon radiation dose of solar greenhouse employees was 2.00 mSv in 2014.T-SOD activity was（ 87.43 ± 15.77） × 10~3 U/L,and MDA concentration was（ 4.36 ±0.62） μmol/L.Multivariate logistic regression analysis results showed that after excluding confounding factors such as gender,age,smoking,alcohol drinking,planting length and pesticide exposure score,the higher the radon exposure dose,the higher risk of abnormalities in T-SOD activity and MDA concentration（ P〈0.05）.Conclusion There is a correlation between radon exposure and oxidative damage effects in solar greenhouse employees.