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基于效应差异探讨中医干预右半结肠癌 被引量:4

Based on the Difference of Biological Effect Explore Chinese Medicine Treating the Right Colon Cancer
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摘要 脾虚作为结肠癌主要病机已得到当代中医学者的广泛认同,而近年西医对左右半结肠的争论愈演愈烈,也让广大中医学者开始关注左右半结肠症状体征差异及这种差异的生理病理机制。较左半结肠癌而言,右半结肠癌腹泻、右腹疼痛、便血、血管侵袭的临床表现更为常见,且有女性高发、胆囊术后患者高发的特点,提示右半结肠癌的病机除脾虚外其关键在于"肝"。肝旺乘侮致腹泻腹痛,肝不藏血致诸多血症,肝失疏泄导致发病人群的特异。故此,右半结肠癌的病机实属土虚木乘、肝脾不和。临证时贯彻"同病异治"的中医思想理论,根据病位辨明病机对结肠癌的诊治意义重大。 It is widely recognized by contemporary Chinese medicine scholars that spleen deficiency was the main pathogenesis of colon cancer,and in recent years,as the debate on left and right half colon intensified,more and more Chinese medicine practitioners began to focus on the left and right semi-colon symptoms and signs of this difference and physiological pathology. Compared with the left colon cancer,in the right colon cancer the Clinical symptoms such as diarrhea,right abdominal pain,hematochezia,vessel invasion,high incidence in female,high incidence in patients after cholecystectomy is more comon,which suggest that except of spleen deficiency that the"liver"also has an important effect in it. Liver exuberance leads to diarrhea and right abdominal pain,liver is not hidden that leads to many blood disorders,deficiency of liver failure leads to the specificity of the population. Therefore,The pathogenesis of right colon cancer is liverspleen dishomony. In clinical practice,implementing the theory of Traditional Chinese Medicine with"Different Diseases of the Same Disease"and identify the pathogenesis according to the disease is great Significant for diagnosis and treatment of colon cancer.
作者 李蒙丽 严然 郑川 祝捷 鱼潇宁 由凤鸣 LI Meng-li;YAN Ran;ZHENG Chuan;ZHU Jie;YU Xiao-ning;YOU Feng-ming(Chengdu University of Traditional Chinese Medicine,Sichuan,Chengdu 610075,China)
机构地区 成都中医药大学
出处 《中国中医基础医学杂志》 CAS CSCD 北大核心 2018年第6期742-744,共3页 JOURNAL OF BASIC CHINESE MEDICINE
基金 国家自然科学基金面上项目(81774284)-痛泻要方干预microRNA214诱导的结肠炎癌演进过程关键分子事件研究 四川省科技厅课题(2017SZ0077)-风药抗肺腺癌侵袭 转移的治法与技术研究
关键词 左右差异 右半结肠癌 肝脾不和 Difference of left and right right colon cancer Liver-Spleen Disharmony
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