脓毒症时糖代谢紊乱的逆转措施研究进展

Progress of therapeutic strategies for glucose metabolic disorders in sepsis

糖代谢紊乱是脓毒症常见问题，可导致病死率增加，然而目前临床上对抗血糖紊乱的手段还有待改善。因此，研究脓毒症时糖代谢紊乱的机制并调整现有的治疗措施对糖代谢紊乱进行逆转十分重要。本文归纳了近几年脓毒症糖代谢方面的动物实验和临床研究进展，重点阐述了对高血糖、低血糖、血糖变异度的改善措施，为脓毒症患者血糖的控制提供新思路。

Glucose metabolic disorder is a common issue in sepsis and it leads to an increase in mortality. However, the therapeutic methods of the glucose metabolic disorders in sepsis patients need to be improved. Studying the mechanism of glucose metabolism disorder, and adjusting the existing treatment measures are especially significant in curing the sepsis. This review summarizes recent animal experiments and clinical studies about glucose change after septic complications, focusing on the treatment of three disorders ineluding hyperglycemia, hypoglycemia, and blood glucose variability. They definitely provide new ideas for the control of blood glucose in sepsis patients.