摘要
目的:运用逼近理想解排序法(TOPSIS)对潞党参的5个指标进行质量的综合评价,以筛选优质潞党参的栽培基地。方法:利用水溶性浸出物测定法、醇溶性浸出物测定法、紫外-可见分光光度法、高效液相色谱法的检测技术,分别测定不同栽培地潞党参中的水溶性浸出物、醇溶性浸出物、总皂苷、党参炔苷、总多糖5个指标含量,并结合熵权TOPSIS数学模型综合评价山西省平顺县潞党参的品质。结果:S1(青羊镇老马岭村)的最优解欧式贴近度(Ci)值为0.837 4,整体质量高于其他栽培基地,而S7(杏城镇黑虎村河湾)的Ci值为0.535 7,相对来说整体质量是较差的。S1,S4(龙溪镇南小沟村驮言角),S6(龙溪镇淙上村)Ci分别为0.837 4,0.824 0,0.810 5,在所有样品中排名前3,表明这3个地点所产药材质量较优,可作为栽培潞党参的优选之地。结论:TOPSIS评价模型是将多维问题转化为一维问题,具有科学性、准确性和客观性,其理论完善、计算简便、易于操作,因此该模型适合用于评价最优的货源基地,为制药企业对潞党参栽培基地的选择提供参考依据。同时此评价模型也可推广应用于其他中药材多指标的综合质量评价。
Objective: To comprehensively evaluate the quality of five indicators of Codonopsis pilosula by using technique for order preferency by similarity to ideal solution(TOPSIS),and select the good cultivation base for C. pilosula. Method: Contents of 5 indexes(water-soluble extracts,alcohol-soluble extracts,total saponins,lobetyolin,and total polysaccharide) for C. pilosula were determined by methods of water-soluble extract determination,alcohol-soluble extract determination, ultraviolet-visible(UV-VIS) spectrophotometry and high performance liquid chromatography(HPLC) in different cultivated lands. Then the entropy TOPSIS mathematical model was used to evaluate the quality of C. pilosula in Pingshun county,Shanxi province. Result: The Civalue of S1(Laomaling village in Qingyang town) was 0. 837 4,with an overall quality superior to other regions; on the contrary,the Civalue of S7(river bay in Heihu village,Xingcheng town) was 0. 535 7,with a relatively poor quality. The Civalues of S1,S4(Xiaogou village,Longxi town),and S6(Congshang village,Longxi town)were top 3 among all the samples(0. 837 4,0. 824 0,0. 810 5 respectively),indicating that these samples in the three regions had better medicinal quality,and these regions could be selected as preferred origins for C. pilosula. Conclusion: The TOPSIS evaluation model could transform multiple dimensions into one dimension,which is scientific,accurate and objective. It is perfect in theory,simple in calculation and easy in operation,so it could be used to evaluate the optimal cultivation base,providing basis for selection of cultivation area for C. pilosula. Meanwhile,this TOPSIS evaluation model could also be applied to the comprehensive evaluation of other traditional Chinese medicines.
作者
黄瑜
秦姣
张德全
叶世碧
黄艳萍
周浓
HUANG Yu;QIN Jiao;ZHANG De-quan;YE Shi-bi;HUANG Yan-ping;ZHOU Nong(College of Pharmacy and Chemistry, Dali University, Dali 671000, China;College of Biology and Food Engineering, The Chongqing Engineering Laboratory for Green Cultivation and Deep Processing of the Three Gorges Reservoir Area's Medicinal Herbs, Municipal Development and Reform Commission, Chongqing Three Gorges University, Chongqing 404120, China)
出处
《中国实验方剂学杂志》
CAS
CSCD
北大核心
2018年第15期77-82,共6页
Chinese Journal of Experimental Traditional Medical Formulae
基金
国家自然科学基金项目(81260622)
关键词
潞党参
栽培基地
多指标分析
质量评价
TOPSIS模型
Codonopsis pilosula
cultivation base
multi-index analysis
quality evaluation
TOPSIS model