肽受体放射性核素治疗在胃肠胰神经内分泌肿瘤中的应用进展

Application of peptide receptor radionuclide therapy for gas-troenteropancreatic neuroendocrine tumor

利用放射性核素标记多肽类似物对肿瘤细胞进行靶向放射治疗的肽受体放射性核素治疗（PRRT）对无法手术的胃肠胰神经内分泌肿瘤患者是一种重要的治疗方式。近年来，随着较多临床试验的开展，研究者对不同核素、新型靶向分子的研究以及对PRRT不良反应的探索，PRRT治疗方案不断发展，对胃肠胰神经内分泌肿瘤的治疗方式和效果产生了较大影响。

Peptide receptor radionuclide therapy （ PRRT）, being investigated as an effective treatment for inoper- able gastroenteropancreatic neuroendocrine tumor, has gained much importance in recent years. With increasing data of clinical trials and the exploration of different radionuclides as well as the toxic and side effects, PRRT has developed continuously and play a marked role on the treatment of gastroenteropancreatic neuroendocrine tumor.