摘要
本讲座主要介绍采用QUIPS(Quality In Prognosis Studies)工具对预后因素研究中出现的偏倚进行评估,介绍相关评估要点,举例说明QUIPS工具的使用,并对该工具在使用中值得商榷的地方进行了讨论。该工具主要涉及研究对象、研究失访、预后因素测量、结局测量、研究混杂以及统计分析和报告6个方面,为预后因素研究中的偏倚评价提供了一个全新的方法。
This paper introduces the tools related to Quality In Prognosis Studies (QUIPS) to assess the risk of bias in studies of prognostic factors and the relevant points of assessment and to illustrate the application of QUIPS in published prognostic research. The QUIPS tool identified 6 important areas to consider when evaluating validity and bias in studies of prognostic factors including participation, attrition, measurement on prognostic factors, outcomes, confounding factors, statistical analysis and reporting. It also provided a new method for evaluation on bias in the areas of prognostic research.
作者
唐少文
张渊
陶必林
杨智荣
孙凤
詹思延
Tang Shaowen;Zhang Yuan;Tao Bilin;Yang Zhirong;Sun Feng;Zhan Siyan(Department of Epidemiology, Nanjing Medical University, Nanjing 211166, China;Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton L8S 4K1, CA;Primary Care Unit, Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridgeshire CBl 8RN, UK;Center of Evidence-based Medicine, Peking University, Beijing 100191, China)
出处
《中华流行病学杂志》
CAS
CSCD
北大核心
2018年第7期1003-1008,共6页
Chinese Journal of Epidemiology
基金
国家自然科学基金(81473067,81373066)
关键词
偏倚风险
评估工具
预后研究
系统综述
Risk of bias
Tool for assessment
Prognosis studies
Systematic review