胎脂和羊毛脂中支链脂肪酸组成的研究

Branched chain fatty acid compositions of vernix caseosa and lanolin

支链脂肪酸(BCFA)是胎脂的重要成分,胎儿吞食羊水可获取胎脂中的BCFA,从而参与发挥肠道的防御作用。早产儿吞食胎脂不足,肠道缺乏BCFA,需要外源补充,羊毛脂是潜在的BCFA的天然来源。对胎脂和羊毛脂的BCFA组成进行分析。结果表明:胎脂含有复杂的脂质种类,主要是非极性脂质;胎脂总脂质和胎脂甘油三酯中的BCFA含量都比较高,依次为17.16%、16.12%;胎脂中共检测到11种BCFA,其中异构C12∶0、异构C14∶0、异构C16∶0、反异构C15∶0的含量较高;羊毛脂的脂肪酸中含有约48.53%的BCFA,包括了胎脂中大部分可测得的BCFA,因此羊毛脂可以模拟胎脂中的BCFA,具有在早产儿配方食品中应用的价值。

Branched chain fatty acids （BCFA）are prominent components of vernix caseosa. They are ob- tained by fetus through the ingestion of amniotic fluid to participate in the role of intestinal tract defense. Preterm infant swalls less amount of vernix caseosa, which makes them be lack of BCFA in intestinal tract,so they need external supplement of BGFA. Lanolin is a potential natural source of BCFA. The BCFA compositions of vernix caseosa and lanolin were analyzed. The results showed that vernix caseosa contained complex lipid species, mainly non - polar lipids. The BCFA contents in total lipids and triglyc- erides in vernix caseosa were 17.16% and 16.12%, respectively. There were eleven kinds of BCFA de- tected in vernix caseosa,in which the contents of i soC12： 0, isoC14： 0, isoC16：0 and anteisoC15：0 were higher. The fatty acid in lanolin contained about 48.53% BCFA, including most BCFA that detected in vernix caseosa, so lanolin could mimic BCFA in vernix caseosa and had the value to be used in formula food of preterm infants.