ω-3多不饱和脂肪酸促眼部健康研究进展

Progress in ω-3 polyunsaturated fatty acids promoting eye health

ω-3多不饱和脂肪酸(ω-3 PUFAs)是视网膜的重要组成成分,对眼部健康有着重要的作用。缺乏ω-3 PUFAs易发多种眼部疾病,如干眼症、视网膜色素变性、青光眼和早产儿视网膜病变等,补充之后可以缓解和预防。着重阐述了ω-3 PUFAs对干眼症、视网膜色素变性、青光眼和早产儿视网膜病变的影响及其可能机制,并提出摄入ω-3 PUFAs的量应适当,且应保持适宜的ω-3 PUFAs与ω-6 PUFAs摄入比例(1∶3~1∶4),以期为研究ω-3 PUFAs促进视觉系统的正常发展提供参考依据。

ω-3 Polyunsaturated fatty acids（ω-3 PUFAs） are the important components of the retina, and they have a unique effect on eye health. Lacking of ω-3 PUFAs is easy to cause a variety of eye dis- eases, such as dry eyes （ DE ）, retinitis pigmentosa （ RP）, glaucoma and retinopathy of prematurity （ROP） ,while it can be relieved and prevented after supplement. The effects of ω-3 PUFAs on DE, RP, glaucoma and ROP and the possible mechanisms were mainly described. It was suggested that the amount of ω-3 PUFAs intake would be appropriate, and a proper intake ratio of ω-3 PUFAs to ω-3 PUFAs （ 1 ： 3 - 1 ： 4） would be kept to ensure the normal development of the visual system.