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糖尿病合并肌痛一例报道 被引量:1

Diabetes mellitus combined with myalgia: A case report
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摘要 目的 本文报道1例老年男性T2DM患者血糖控制不佳,无明显诱因出现左下肢肌肉疼痛,血肌酸激酶(CK)升高,核磁共振(MRI)提示左股二头肌短头、比目鱼肌异常信号,增强扫描后可见均匀强化,诊断为糖尿病肌病。经休息、胰岛素降糖等治疗,患者疼痛好转,CK下降,MRI肌肉异常信号消失。糖尿病肌病是较少见糖尿病并发症,常出现于血糖控制不良患者,临床上极易被忽视,需早期诊断治疗,避免发展至坏死性筋膜炎、脓性肌炎等严重并发症。 This case report described an old man with poorly controlled type 2 diabetes mellitus(T2DM)who presented with pain in the left thigh without obvious inducing factors and elevated creatine phosphokinase(CK).Further examination with magnetic resonance imaging(MRI)revealed a high intensity signal in the left caput breve biceps femoris and soleus.The patient was diagnosed with diabetic myopathy and treated with bed rest and insulin.After that,his muscle pain relieved,CK level decreased and the abnormal signal in MRI disappeared.Diabetic myopathy is a rare diabetic complication associated with poor glycemic control,which may probably develop to necrotizing fasciitis,purulent myositis or other serious complications without early diagnosis and treatment.
作者 陆冰 胡秋菊 刘晔 金东生 陈吉海 欧阳晓俊 LU Bing;HU Qiuju;LIU Ye;OUYANG Xiaojun(Department of Senile Weakness and Nutritional Metabolism Laboratory,Jiangsu Province Geriatric Hospital,Nanjing 210024,China)
出处 《中国糖尿病杂志》 CAS CSCD 北大核心 2018年第7期605-607,共3页 Chinese Journal of Diabetes
基金 江苏省"六大人才高峰"资助项目(2015-WSN-018)
关键词 糖尿病 糖尿病肌病 糖尿病肌肉梗死 糖尿病肌坏死 Diabetes mellitus Diabetic myopathy Diabetic muscle infarction Diabetes myonecrosis
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  • 1Trujillo-Santos AJ.Diabetic muscle infarction:an underdiagnosed complication of long-standing diabetes.Diabetes Care,2003,26:211-215.
  • 2Scully RE,Mark EJ,Mcneely WF,et.al.Case records of the Massachusetts General Hospital.Weekly clinicopathological exercises.Case 20-1997.A 54-year-old diabetic woman with pain and swelling of the leg.N Engl J Med,1997,337:839-845.
  • 3Bjornskov EK,Carry MR,Katz FH,et al.Diabetic muscle infraction:a new perspective on pathogenesis and management.Neuromuscul Disord,1995,5:39-45.
  • 4Palmer GW,Greco TP.Diabetic thigh muscle infarction in association with antiphospholipid antibodies.Semin Arthritis Rheum,2001,30:272-280.

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