生殖支原体在男性泌尿生殖相关疾病中的研究进展

Mycoplasma genitalium and male urogenital diseases: An update

生殖支原体(MG)是由Tully在1981年首次从男性非淋菌性尿道炎(NGU)患者的泌尿道中分离出来的新的支原体。MG培养极其困难,直到分子生物学技术的发展与应用,才出现大量相关研究,目前国内处于起步探索阶段,但是国外已研究发现其是人类泌尿生殖道感染的重要病原体,且呈全球蔓延之势。据报道,男性MG感染与NGU、前列腺炎、附睾炎、包皮阴茎头炎、男性人类免疫缺陷病毒(HIV)感染及男性不育等有关,本文就其在男性泌尿生殖相关疾病中的研究进展进行综述。

Mycoplasma genitalium（ MG） was first isolated by Tully from the urinary tract of the male patient with non-gonococcal urethritis（ NGU） in 1981. MG is extremely difficult to be cultured and was rarely studied until the development and application of molecular biology technology. The research on MG in China is still in the primary stage. However,relevant studies abroad have found that it is an important pathogen causing human genitourinary tract infection and spreading worldwide. Male MG infection is reportedly related to NGU,prostatitis,epididymitis,balanoposthitis,male HIV infection,and male infertility. This review outlines the advances in the studies of MG in male urogenital diseases.