穴位贴敷吴茱萸粉加生姜汁防治全膝关节置换术后恶心呕吐临床观察

Clinical Observation on Point Application of Fructus Evodiae Powder Plus Succus Rhizomatis Zingiberis in Preventing and Treating Post-operative Nausea and Vomiting after Total Knee Arthroplasty

目的:观察穴位贴敷吴茱萸粉加生姜汁防治全膝关节置换术(TKA)术后恶心呕吐(PONV)的临床疗效。方法:将240例行TKA治疗的患者随机分为观察组和对照组各120例。对照组术中予格拉司琼治疗,术后予常规护理,并根据世界卫生组织PONV反应分级标准选用甲氧氯普胺片止呕。观察组在对照组基础上于术后进行穴位贴敷吴茱萸粉加生姜汁。记录2组患者PONV发生情况及甲氧氯普胺片使用情况。结果:术后6 h、24 h,观察组恶心呕吐发生率均低于对照组,恶心呕吐程度均轻于对照组,差异均有统计学意义(P<0.05,P<0.01)。术后48 h,2组恶心呕吐发生率及恶心呕吐程度比较,差异均无统计学意义(P>0.05)。术后6 h,2组甲氧氯普胺片使用率比较,差异有统计学意义(P<0.05)。术后24 h、48 h,2组甲氧氯普胺片使用率比较,差异均无统计学意义(P>0.05)。结论:穴位贴敷吴茱萸粉加生姜汁可减少TKA患者PONV发生,减轻PONV程度。

Objective： To observe the clinical effect of point application of Fructus Evodiae powder plus Succus Rhizomatis Zingiberis in preventing and treating post-operative nausea and vomiting（PONV） after total knee arthroplasty（TKA）. Methods：Divided240 cases of patient with TKA into the observation group and the control group randomly,120 cases in each group. The control group was treated with granisetron and received routine nursing after operation. According to the grading standard of PONV reaction from world health organization, methoxychloropramine tablets were selected to prevent vomiting. The observation group was additionally treated with point application of Fructus Evodiae powder plus Succus Rhizomatis Zingiberis based on the treatment of the control group.Recorded the occurrence of PONV and the use of methoxyclopramide tablets in the two groups after treatment. Results：At the 6 th and24 thhours after operation,the incidence of nausea and vomiting in the observation group was lower than that in the control group and the degree of nausea and vomiting was lower,differences being significant（P〈0.05,P〈0.01）. At the 48 th hour after operation,there was no significant difference being found in the comparisons of the incidence of nausea and vomiting and the degree of nausea and vomiting between the two groups（P〉0.05）. At the 6 thhour after operation,the comparison of the use rate of methoxyclopramide tablets between the two groups showed significance in the difference（P〈0.05）. At the 24 thand 48 thhours after operation, there was no significant difference being found in the comparison of the use rate of methoxyclopramide tablets between the two groups（P〉0.05）.Conclusion：The therapy of point application of Fructus Evodiae powder plus Succus Rhizomatis Zingiberis can reduce the occurrence of PONV in patients with TKA and reduce the degree of PONV.