昆明市美沙酮维持治疗患者非法物质使用和生活质量状况调查分析

Concurrentdruguse and quality of life in drug users in methadone maintenance treatment in Kunming, Yunnan Province

目的 :探索美沙酮维持治疗开展10余年来,门诊患者目前的物质使用情况和生活质量。方法 :通过方便抽样的方法,采用自制问卷和生活质量综合评定问卷(GQOL-74),对132名门诊患者进行调查。结果:(1)25.0%(33人)的患者存在着非法物质使用情况,其中,3.0%(1人)有共用针具注射行为,9.1%(3人)患者共用其他注射用品;(2)非法物质使用和人口学特征、治疗状况、HIV感染等因素无关联;(3)生活质量总分为(49.0±3.7)分,各维度分大多在40-60分之间;(4)年轻者(r=-0.321,p<0.001)和已婚者(r=-0.174,p<0.05)总体生活质量相对较好,独居者(r=-0.186,p<0.05)、HIV感染者/AIDS病人(r=-0.198,P<0.05),生活质量总体得分相对较低。结论:美沙酮维持治疗患者中,大约25%的患者存在使用非法物质情况。门诊患者在接受治疗数年后,生活质量整体水平仍然较低。

Objective： To explore the concurrent drug use and quality of life in drug users undergoing methadone maintenance treatment（MMT） in Kunming city 10 more years after the initiation of MMT. Methods： Based on clinic-based sampling method, 132 MMT clients were investigated by employing the self-administrated questionnaire and Generic Quality of Life Inventory-74（GQOLI-74）. Results：（1） 25.0%（33） subjects reported concurrent drug use. Among them, 1（3.0%）subject shared the syringes/needles with peers and 3（9.1%） subjects shared other injection supplies.（2） There is no relationship between concurrent drug use and the characteristics of demographics, duration in treatment, dosage of methadone and HIV infections.（3） The mean of the standardized total score of GQOLI-74 was 49.0±3.7, the range of the standardized scores for 4 domains were about 40-60.（4） younger（r=-0.321,p0.001） and married people（r=-0.174,p0.05） have a higher quality of life, single inhabitants（r=-0.186,p0.05） and HIV-infected MMT clients/AIDS patients（r=-0.198,P0.05） have a lower quality of life. Conclusion：Around 25% MMT clients use illicit drugs concurrently, and their qualities of life are quite poor after years of MMT.