多囊卵巢综合征合并代谢综合征患者卵巢超声指标与内分泌代谢指标的关系

Relationship between ultrasonographic indexes and endocrine metabolism parameters of patients with polycystic ovary syndrome and metabolic syndrome

目的:探讨多囊卵巢综合征(PCOS)合并代谢综合征(MS)患者卵巢超声指标与内分泌、代谢指标的关系。方法:选取2016年2月—2017年12月本院就医的PCOS合并MS患者126例为观察组,并选择基础体温双相的不孕症患者60例为对照组,采集两组患者超声检查、基础生殖激素指标并分析两者相关性。结果:观察组卵泡数目(FN)、卵巢间质面积(SA)、卵巢总面积(TA)、子宫动脉阻力指数(RI)均大于对照组,卵巢间质动脉RI小于对照组,促卵泡生成素(FSH)、促黄体生成素(LH)均低于对照组,睾酮(T)高于对照组(P<0.05);卵巢测量TG、TC、LDL-C、FPG、FINS、HOA-IR指数均高于对照组,HDL-C低于对照组(P<0.05)。FN与T、BMI呈正相关,SA、TA与T呈正相关,子宫动脉RI与BMI呈正相关,卵巢间质动脉RI与FINS、HOMA-IR、BMI呈负相关。对照组未发现超声指标与内分泌指标相关性。结论:PCOS合并MS患者超声指标和内分泌代谢指标均具有一定特征性和相关性,可作为诊断和预测POCS合并MS预后的指标。

Objective：To explore the relationship between ultrasound indexes and endocrine metabolism parameters of patients with polycystic ovary syndrome（PCOS）and metabolic syndrome（MS）.Methods：A total of 126 patients with PCOS and MS who had admitted to the first people＇s hospital of Wutai county from February 2016 to December 2017 were selected into observation group,and another 60 infertile patients with two way of basal body temperature were selected into control group.Ultrasound examination indexes and endocrine metabolism parameters of all patients were collected,and their correlations were analyzed.Results：The follicle number（FN）,ovarian stromal area（SA）,total ovarian area（TA）,and uterine artery resistance index（RI）of patients in observation group were significant more than those of women in control group,but ovarian stromal artery RI of patients in observation group was significant less than that of women in control group.The levels of follicle stimulating hormone（FSH）and luteinizing hormone（LH）of patients in observation group were significant lower than those of women in control group,but level of testosterone（T）of patients in observation group was significant higher than that of women in control group（P〈0.05）.The level of TG,TC,LDL-C,FPG,FINS,and HOA-IR indexes of patients in observation group were significant higher than those of women in control group,but level of HDL-C testosterone（T）of patients in observation group was significant higher than that of women in control group（P〈0.05）.In observation group,there was positive correlation between FN and Tor BMI.There were also positive correlation between SA or TA and T.Uterine artery RI had positively correlated with BMI.Ovarian interstitial artery RI had negatively correlated with FINS,HOMA-IR,or BMI.In control group,there was no correlation between ultrasonographic indexes and endocrine metabolism parameters.Conclusion：The patients with PCOS and MS have certain characteristics in ultrasonographic indexes and endocrine metabolism parameters,and their ultrasonographic indexes have correlations with endocrine metabolism parameters,which can be used to diagnose and foretell the prognosis of patients with POCS and MS.