孕早期强化干预对妊娠期糖尿病患者妊娠结局的效果

Effect of intensive comprehensive intervention on pregnant outcomes of pregnant women with gestational diabetes mellitus when early pregnant stage

目的:探讨早期强化综合干预妊娠期糖尿病(GDM)患者对母婴妊娠结局的影响。方法:选择2016年1月—2017年7月入连云港市第一人民医院诊断GDM患者共120例(孕24~28周),其中常规干预组50例和早期干预组70例。早期干预组于孕早期建卡时即进行干预,包括定期监测血糖、饮食控制、运动指导和胰岛素治疗;对比两组分娩孕周和母婴妊娠结局。结果:早期干预组分娩孕周(39.5±0.8周)大于常规干预组(38.2±1.3周),妊娠并发症发生率(4.3%)和新生儿并发症发生率(5.7%)均低于常规干预组(16.0%、18.0%)(P<0.05)。结论:GDM患者早期强化综合干预可显著改善母婴妊娠结局。

Objective：To explore clinical value of intensive comprehensive intervention on pregnant outcomes of pregnant women with gestational diabetes mellitus（GDM）when early pregnant stage.Method：A total of 120 pregnant women with GDM at 24-28 gestation weeks who admitted to the first people＇s hospital of Lianyungang city from January 2016 to July 2017 were enrolled,and were randomly assigned to common intervention group（n=50）or early intervention group（n=70）.The pregnant women in early intervention group had received intervention from starting pregnancy examination in early pregnancy stage,which included regular monitoring of blood glucose,diet control,exercise guidance and insulin therapy.The gestational weeks when labor and pregnant outcomes of maternal and child were compared between the two groups.Results：The gestational weeks when labor of women in early intervention group（39.5±0.8 weeks）was significant longer than that of women in common intervention group（38.2±1.3 weeks）,and the rates of complication of maternal and child in early intervention group（4.3%,5.7%）were much lower than those（16.0%,18.0%）in early intervention group（P〈0.05）.Conclusion：Intensive comprehensive intervention can greatly improve maternal and child outcomes of pregnant women with GDM.