摘要
大叶钩藤(Uncaria macrophylla Wall)枝干用甲醇提取,利用硅胶柱层析、Sephadex LH-20柱层析和反相柱层析进行化学成分分离纯化,从中分离得到8个化合物.根据现代波谱技术和理化性质对化合物结构进行鉴定,鉴定结构为:熊果酸(1)、齐墩果酸(2)、羽扇豆烯酮(3)、β-谷甾醇(4)、胡萝卜苷(5)、表儿茶素(6)、东莨菪素(7)和3,4-二羟基苯甲酸乙酯(8).
Eight compounds were obtained by silica gel chromatography, Sephadex LH-20 chromatography and reversed-phase chromatography from the methanol extract of the twigs of Uncaria macrophylla Wall. The chemical structures of these compounds were identified by modern spectroscopic analysis combined with their physico-chemical data. These compounds were identified to be ursolic acid (1), oleanolic Acid (2), lupenone (3), β -sitosterol (4), daucosterol (5), epicatechin (6), scopoletin (7), and ethyl 3,4-dihydroxybenzoate (8).
作者
杨敏超
朱惠
段志航
陈业高
YANG Minchao;ZHU hui;DUAN Zhihang;CHEN Yegao(School of Chemistry and Chemical Engineering,Yunnan Normal University,Kunming 650500,Chin)
出处
《海南师范大学学报(自然科学版)》
CAS
2018年第2期139-142,150,共5页
Journal of Hainan Normal University(Natural Science)
基金
云南省高校药用活性分子结构多样性研究重点实验室(2016-5)
关键词
大叶钩藤
化学成分
结构鉴定
Uncaria macrophylla
chemical constituents
structure identification